Jun Seita's Web

Comprehensive methylome map of lineage commitment from haematopoietic progenitors.

Ji H*, Ehrlich LI*, Seita J* (*equally contributed), Murakami P, Doi A, Lindau P, Lee H, Aryee MJ, Irizarry RA, Kim K, Rossi DJ, Inlay MA, Serwold T, Karsunky H, Ho L, Daley GQ, Weissman IL, Feinberg AP

Nature 2010 Aug 15; Advanced Online Publication

PMID: 20720541

Differential DNA Damage Response in Stem and Progenitor Cells.

Seita J, Rossi DJ, Weissman IL.

Cell Stem Cell. 2010 Aug 6;7(2):145-147. [Preview]

PMID: 20682442

Epigenetic memory in induced pluripotent stem cells.

Kim K, Doi A, Wen B, Ng K, Zhao R, Cahan P, Kim J, Aryee MJ, Ji H, Ehrlich LI, Yabuuchi A, Takeuchi A, Cunniff KC, Hongguang H, McKinney-Freeman S, Naveiras O, Yoon TJ, Irizarry RA, Jung N, Seita J, Hanna J, Murakami P, Jaenisch R, Weissleder R, Orkin SH, Weissman IL, Feinberg AP, Daley GQ

Nature 2010 Jul 19; Advanced Online Publication

PMID: 20644535

Hematopoietic stem cell: self-renewal versus differentiation.

Seita J, Weissman IL

WIREs Systems Biology and Medicine Published Online: Apr 01 2010, DOI: 10.1002/wsbm.86

WILEY Interdisciplinary Reviews Site

MiDReG: A method of mining developmentally regulated genes using Boolean implications.

Sahoo D, Seita J, Bhattacharya D, Inlay MA, Weissman IL, Plevritis SK, and Dill DL.

PNAS published online before print March 15, 2010, doi:10.1073/pnas.0913635107

PMID: 20231483

Press release from Stanford

Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development.

Inlay MA, Bhattacharya D, Sahoo D, Serwold T, Seita J, Karsunky H, Plevritis SK, Dill DL, Weissman IL.

Genes Dev. 2009 Oct 15;23(20):2376-81.

PMID: 19833765

Establishment of a Normal Hematopoietic and Leukemia Stem Cell Hierarchy.

Chao MP, Seita J, Weissman IL.

Cold Spring Harb Symp Quant Biol. 2008;73:439-49. Epub 2008 Nov 6.

PMID: 19022770

Interleukin-27 directly induces differentiation in hematopoietic stem cells.

Seita J, Asakawa M, Ooehara J, Takayanagi S, Morita Y, Watanabe N, Fujita K, Kudo M, Mizuguchi J, Ema H, Nakauchi H, Yoshimoto T.

Blood. 2008 Feb 15;111(4):1903-12. Epub 2007 Nov 27.

PMID: 18042804

Hematopoietic Stem Cell Quiescence Attenuates DNA Damage Response and Permits DNA Damage Accumulation During Aging.

Rossi DJ, Seita J, Czechowicz A, Bhattacharya D, Bryder D, Weissman IL.

Cell Cycle 2007 Oct 1;6(19):2371-6. Epub 2007 Jul 18.

PMID: 17700071

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age.

Rossi DJ*, Bryder D*, Seita J, Nussenzweig A, Hoeijmakers J, Weissman IL (*: equally contributed).

Nature 2007 Jun 7;447(7145):725-9.

PMID: 17554309

Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction.

Seita J, Ema H, Ooehara J, Yamazaki S, Tadokoro Y, Yamasaki A, Eto K, Takaki S, Takatsu K, Nakauchi H.

Proc Natl Acad Sci U S A 2007 Feb 13;104(7):2349-54. Epub 2007 Feb 6.

PMID: 17284614

Adult mouse hematopoietic stem cells: purification and single-cell assays.

Ema H, Morita Y, Yamazaki S, Matsubara A, Seita J, Tadokoro Y, Kondo H, Takano H, Nakauchi H.

Nature Protocols 2006;1(6):2979-87.

PMID: 17406558

Quantification of self-renewal capacity in single hematopoietic stem cells from normal and Lnk-deficient mice.

Ema H, Sudo K, Seita J, Matsubara A, Morita Y, Osawa M, Takatsu K, Takaki S, Nakauchi H.

Dev Cell 2005 Jun;8(6):907-14.

PMID: 15935779